Foye医药学原理Foye＇s Principles of Medicinal Chemistry mobi 下载 网盘 caj lrf pdf txt 阿里云

This comprehensive Fifth Edition has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. The new emphasis is on pharmaceutical care that focuses on the patient, and on the pharmacist a therapeutic clinical consultant, rather than chemist. Approximately 45 contributors, respected in the field of pharmacy education, augment this exhaustive reference. New to this edition are chapters with standardized formats and features, such as Case Studies, Therapeutic Actions, Drug Interactions, and more. Over 700 illustrations supplement this must-have resource.

Massachusetts College of Pharmacy and Health Sciences, Boston. Textbook, for pharmacy students, now includes an overview of the drug development process from the perspective of an industrial research scientist. Also new to this edition: an overview of drug receptors, case studies, selected readings, and a companion web page. Previous edition: c1995.

Introduction Origins of Medicinal Chemistry

Part Ⅰ Principles of Drug Discovery

　Overview Drug Design and Development: A Perspective

　1. Natural Products

　 2. Drug Design and Relationship of Functional Groups to Pharmacologic Activity

　3. Molecular Modeling and Drug Design

　 4. Receptors and Drug Action

　5. Drug Design Through Enzyme Inhibition

　 6. Peptide and Protein Drugs

　7. Physicochemical and Biopharmacemical Properties of Drug Substances and Pharmacokinetics

　 8. Drug Metabolism

　9. U.S. Drug Regulation: An Overview

Part Ⅱ Pharmacodynamic Agents

Overview Drug Receptors: A Perspective

　Section 1 Drugs Affecting Neurotransmission

　　10. Drugs Affecting Cholinergic Neurotransmission

　　11. Drugs Affecting Adrenergic Neurotransmission

　　12. Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission

　　13. Local Anesthetics

　Section 2 Drugs Affecting Central Nervous System

　　14. Volatile Anesthetics

　　15. Hypnotics

　　16. Antiseizure Drugs

　　17. Psychotherapeutic Drugs: Antipsychotic and Anxiolytic Agents

　　18. Hallucinogens, Stimulants, and Related Drugs of Abuse

　　19. Opioid Analgesics

　　20. Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents

　Section 3 Drugs Affecting the Cardiovascular System

　　21. Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs

　　22. Diuretics

　　23. Angiotensin Converting Enzyme Inhibitors, Antagonists and Calcium Blockers

　　24. Central and Peripheral Sympatholytics and Vasodilators

……

Part Ⅲ Recent Advances in Drug Discovery

Appendices pKa Values for Some Drugs and Miscellaneous Organic Acids and Bases pH Values for Tissue Fluids

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